Zero-Mode Contribution in Nucleon-Delta Transition

We investigate the transition form factors between nucleon and $\Delta$(1232) particles by using a covariant quark-spectator-diquark field theory model in (3+1) dimensions. Performing a light-front calculation in parallel with the manifestly covariant calculation in light-front helicity basis, we examine the light-front zero-mode contribution to the helicity components of light-front good ("+") current matrix elements. Choosing the light-front gauge ($\epsilon^+_{h=\pm}=0$) with circular polarization in Drell-Yan-West frame, we find that only the helicity components $({1\over 2}, {1\over 2})$ and $({1\over 2},-{1\over 2})$ of the good current receive the zero-mode contribution. Taking into account the zero-mode, we find the prescription independence in obtaining the light-front solution of form factors from any three helicity matrix elements with smeared light-front wavefunctions. The angular condition, which guarantees the full covariance of different schemes, is recovered.Comment: 16 latex pages, 7 figures, to appear in PR

Non-local tensor completion for multitemporal remotely sensed images inpainting

Remotely sensed images may contain some missing areas because of poor weather conditions and sensor failure. Information of those areas may play an important role in the interpretation of multitemporal remotely sensed data. The paper aims at reconstructing the missing information by a non-local low-rank tensor completion method (NL-LRTC). First, nonlocal correlations in the spatial domain are taken into account by searching and grouping similar image patches in a large search window. Then low-rankness of the identified 4-order tensor groups is promoted to consider their correlations in spatial, spectral, and temporal domains, while reconstructing the underlying patterns. Experimental results on simulated and real data demonstrate that the proposed method is effective both qualitatively and quantitatively. In addition, the proposed method is computationally efficient compared to other patch based methods such as the recent proposed PM-MTGSR method

Revisiting Disentanglement and Fusion on Modality and Context in Conversational Multimodal Emotion Recognition

It has been a hot research topic to enable machines to understand human emotions in multimodal contexts under dialogue scenarios, which is tasked with multimodal emotion analysis in conversation (MM-ERC). MM-ERC has received consistent attention in recent years, where a diverse range of methods has been proposed for securing better task performance. Most existing works treat MM-ERC as a standard multimodal classification problem and perform multimodal feature disentanglement and fusion for maximizing feature utility. Yet after revisiting the characteristic of MM-ERC, we argue that both the feature multimodality and conversational contextualization should be properly modeled simultaneously during the feature disentanglement and fusion steps. In this work, we target further pushing the task performance by taking full consideration of the above insights. On the one hand, during feature disentanglement, based on the contrastive learning technique, we devise a Dual-level Disentanglement Mechanism (DDM) to decouple the features into both the modality space and utterance space. On the other hand, during the feature fusion stage, we propose a Contribution-aware Fusion Mechanism (CFM) and a Context Refusion Mechanism (CRM) for multimodal and context integration, respectively. They together schedule the proper integrations of multimodal and context features. Specifically, CFM explicitly manages the multimodal feature contributions dynamically, while CRM flexibly coordinates the introduction of dialogue contexts. On two public MM-ERC datasets, our system achieves new state-of-the-art performance consistently. Further analyses demonstrate that all our proposed mechanisms greatly facilitate the MM-ERC task by making full use of the multimodal and context features adaptively. Note that our proposed methods have the great potential to facilitate a broader range of other conversational multimodal tasks.Comment: Accepted by ACM MM 202

Does PGA external stenting reduce compliance mismatch in venous grafts?

BACKGROUND: Autogenous vein grafting is widely used in regular bypassing procedures. Due to its mismatch with the host artery in both mechanical property and geometry, the graft often over expands under high arterial blood pressure and forms a step-depth where eddy flow develops, thus causing restenosis, fibrous graft wall, etc. External stents, such as sheaths being used to cuff the graft, have been introduced to eliminate these mismatches and increase the patency. Although histological and immunochemical studies have shown some positive effects of the external stent, the mechanical mismatch under the protection of an external stent remains poorly analyzed. METHODS: In this study, the jugular veins taken from hypercholesterolemic rabbits were transplanted into the carotid arteries, and non-woven polyglycolic acid (PGA) fabric was used to fabricate the external stents to study the effect of the biodegradable external stent. Eight weeks after the operation, the grafts were harvested to perform mechanical tests and histological examinations. An arc tangent function was suggested to describe the relationship between pressure and cross-sectional area to analyse the compliance of the graft. RESULTS: The results from the mechanical tests indicated that grafts either with or without external stents displayed large compliance in the low-pressure range and were almost inextensible in the high-pressure range. This was very different from the behavior of the arteries or veins in vivo. The data from histological tests showed that, with external stents, collagen fibers were more compact, whilst those in the graft without protection were looser and thicker. No elastic fiber was found in either kind of grafts. Furthermore, grafts without protection were over-expanded which resulted in much bigger cross-sectional areas. CONCLUSION: The PGA external extent contributes little to the reduction of the mechanical mismatch between the graft and its host artery while remodeling develops. For the geometric mismatch, it reduces the cross-section area, therefore matching with the host artery much better. Although there are some positive effects, conclusively the PGA is not an ideal material for external stent.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

The changes of cardiac energy metabolism with sodium-glucose transporter 2 inhibitor therapy

Background/aimsTo investigate the specific effects of s odium-glucose transporter 2 inhibitor (SGLT2i) on cardiac energy metabolism.MethodsA systematic literature search was conducted in eight databases. The retrieved studies were screened according to the inclusion and exclusion criteria, and relevant information was extracted according to the purpose of the study. Two researchers independently screened the studies, extracted information, and assessed article quality.ResultsThe results of the 34 included studies (including 10 clinical and 24 animal studies) showed that SGLT2i inhibited cardiac glucose uptake and glycolysis, but promoted fatty acid (FA) metabolism in most disease states. SGLT2i upregulated ketone metabolism, improved the structure and functions of myocardial mitochondria, alleviated oxidative stress of cardiomyocytes in all literatures. SGLT2i increased cardiac glucose oxidation in diabetes mellitus (DM) and cardiac FA metabolism in heart failure (HF). However, the regulatory effects of SGLT2i on cardiac FA metabolism in DM and cardiac glucose oxidation in HF varied with disease types, stages, and intervention duration of SGLT2i.ConclusionSGLT2i improved the efficiency of cardiac energy production by regulating FA, glucose and ketone metabolism, improving mitochondria structure and functions, and decreasing oxidative stress of cardiomyocytes under pathological conditions. Thus, SGLT2i is deemed to exert a benign regulatory effect on cardiac metabolic disorders in various diseases.Systematic review registrationhttps://www.crd.york.ac.uk/, PROSPERO (CRD42023484295)

Epidemiological investigation and analysis of Clostridium perfringens food poisoning caused by food delivery

Objective To find out the suspicious food, pathogenic factors and risk factors of a foodborne disease outbreak in a factory, and to discuss the problems exposed in the investigation of the incident, so as to provide reference for the prevention, control and investigation of similar incidents in the future. Methods A case was defined as the onset of abdominal pain or diarrhea (≥3 times/24 hours) or vomiting in a person who worked in M factory from March 3 to March 4 in 2019. Case interviews and retrospective research was carried out using descriptive and analytical epidemics pathological method. Stool specimens of the cases, leftover food and related environmental samples were gathered for pathogen isolation and toxin gene detection using polymerase chain reaction (PCR). Results 106 cases were identified with a attack rate of 73.6% (106/144). The symptoms were diarrhea (78.3%, 83/106), abdominal cramps (78.3%, 83/106), abdominal gas pains (9.4%, 10/106), and no fever. The epidemic curve showed a point source exposure pattern. The median incubation time was 10 hours (range: 2-22 h). Illness were associated with three food items of the lunch on March 3 in 2019 by univariate analysis and Logistic regression analysis: braised fish pieces [relative risk (RR)=1.55, 95% confidence interval (95%CI): 1.29-1.85], pork stir-fried with garlic sprouts (RR=1.26, 95%CI: 1.01-1.57) and duck blood stir-fried with pickles (RR=1.47, 95%CI: 1.16-1.87). Alpha toxin and enterotoxin CPE genes were positive and beta toxin genes was negative in the Clostridium perfringens strain isolated in anal swabs of three patients, three environmental samples and two leftover food samples. There were possible bacterial contamination and reproduction in the processing and preparation of enterprise D, which delivered food. Conclusion This incident was caused by the food poisoning of Clostridium perfringens caused by the consumption of a meal provided by a catering company. After the meal was delivered, it should be cooled quickly and stored at low temperature. If it cannot be eaten immediately, it should be heated sufficiently before eating

Cell-Free Mitochondrial DNA in the CSF: A Potential Prognostic Biomarker of Anti-NMDAR Encephalitis

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune inflammatory brain disease that can develop a variety of neuropsychiatric presentations. However, the underlying nature of its inflammatory neuronal injury remains unclear. Mitochondrial DNA (mtDNA) is recently regarded as a damage-associated molecular pattern molecule (DAMP) that can initiate an inflammatory response. In the presenting study, we aimed to evaluate the levels of cell-free mtDNA in cerebrospinal fluid (CSF) of patients with anti-NMDAR encephalitis and to determine a potential role of cell-free mtDNA in the prognosis of anti-NMDAR encephalitis. A total of 33 patients with NMDAR encephalitis and 17 patients with other non-inflammatory disorders as controls were included in this study. The CSF levels of cell-free mtDNA were measured by quantitative polymerase chain reaction (qPCR). Cytokines including interleukin (IL)-6, IL-10, and tumor necrosis factor alpha (TNF-α) were measured by ELISA. The modified Rankin scale (mRS) score was evaluated for neurologic disabilities. Our data showed that the CSF levels of cell-free mtDNA and inflammation-associated cytokines were significantly higher in the patients with anti-NMDAR encephalitis compared with those in controls. Positive correlations were detected between the CSF levels of cell-free mtDNA and mRS scores of patients with anti-NMDAR encephalitis at both their admission and 6-month follow up. These findings suggest that the CSF level of cell-free mtDNA reflects the underlying neuroinflammatory process in patients with anti-NMDAR encephalitis and correlates with their clinical mRS scores. Therefore, cell-free mtDNA may be a potential prognostic biomarker for anti-NMDAR encephalitis

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<p>Tertiary interactions and base triples are illustrated with continuous lines. Base-pairing is indicated as follows: Watson-Crick pairs, lines; GU pairs, dots; other non-canonical pairs, circles.</p